Filenews 1 July 2021
New side effects arise as more people are vaccinated against the pandemic coronavirus, but the good news is that they remain rare, they can be managed, while coronavirus disease can bring the same results in some cases.
These data are derived from the latest studies published or pre-published online in the last month, as well as from a recent unpublished comparative analysis by the European Medicines Agency on the side effects of vaccines against natural cognition from coronavirus.
The relevant data were presented by the Doctor of Medicine candidate of the Democritus University of I. Petrakis and Xavier Kurtz, head of the data analysis department of the European Medicines Agency (EMA) and the European Network of the Centres for Pharmacoepidemiology and Pharmacovigilance of EMA, on the last day of the conference of the Hellenic Society of Pharmaceutical Medicine (ELEFI).
Unwanted side effects
In particular, according to the latest publications, Mr Petrakis mentioned that undesirable side effects include stroke – haemorrhagic and non-bleeding, infuse, deep vein thrombosis, pulmonary embolism, anaphylaxis, myocarditis – pericarditis, narcolepsy, appendicitis, immune thrombocytopenia, encephalomyelitis, transverse myelitis, Bell's paralysis in the face, diffuse intraceal coagulation and Guilin Barre syndrome.
He noted, however, that "the question that arises in the first place is what about those that have not been recorded, but also how effective their management is, because it is important that they can be treated – which is already the case especially with cases of myocarditis that have alarmed the population, although in the USA there are 1226 reports of myocarditis, when more than 300 million people have been allocated. doses of mRNA vaccines'.
On the part of the European Medicines Agency (EMA), Mr Xavier Kurtz pointed out that as early as April 2020 the Agency was preparing standards of protocols for monitoring vaccinated people and ensuring the health of citizens, which concerned the safety, efficacy and coverage of the population. These standards have been in place since December last year, before vaccinations began.
Of course, there were no epidemiological studies – which followed, with the possibility of stratification of the different characteristics of the population by age group, sex, etc.
Disease versus vaccination
But Then Mr. Kurtz noted that three groups of patients were created, the first the one that diseased the other two vaccines, Pfizer and AstraZeneca, which measured the effects of both the disease and vaccinations with the two vaccines separately.
According to Mr Kurtz, the data collected so far show that deep vein thrombosis is much more common in cases of disease from the pandemic virus compared to vaccination with whichever vaccines and the risk of thromboembolism is even greater. Clearly more likely are the chances of heart attack or cerebral and immune thrombocytopenia, while marginally more are the chances of thrombocytopenia from the AstraZeneca vaccine versus the natural disease or Pfizer vaccine.
Prevention of intensive care
This was followed by a comparison of the benefit and impact of vaccination in preventing hospitalisation and intensive care due to critical disease, based on epidemiological data.
In particular with regard to the AstraZeneca vaccine, it was found that after a dose of vaccine, hospitalization in intensive care for a significant portion of the population aged 50 years and over was prevented, with the greatest benefit being from the ages of 80 and over. In detail, per 100,000 population it was found that hospitalization in intensive care of 6 persons aged 20-29 years was prevented, 8 aged 30-39 years, 15 persons aged 40-49 years, 28 persons 50-59 years old, 50 persons 60-69 years old, 78 persons aged 70-79 years and 110 persons aged 80 years and over.
It was also found that compared to natural disease from the virus, vaccination with both vaccines posed minimal risks of thromboembolic events, namely: with the AstraZeneca vaccine the risk was 0.0017%, Pfizer's 0.0026% and The Natural Disease 0.1897%.
Source: in.gr
